Next-Generation HA Fillers for Naturally Refreshed Skin
The First Cold-X™ Technology Fillers, Layered for Authentic Results at FACE Medspa Smooth smile lines and restore youthful volume without looking “done.” Evolysse is the first line of hyaluronic acid fillers made with revolutionary Cold-X™ Technology, preserving the natural HA structure for softer, more natural movement in expressive facial areas. At FACE Medspa, our award-winning team applies Evolysse can also be the final layer of our proprietary 3D FACE Approach, after regenerating your skin from within, so results look refreshed, harmonious, and authentically you.
“For too long, patients have walked away from filler appointments looking stiff, overfilled, or simply not like themselves, the dreaded ‘pillow face’ that announces you’ve had work done. The problem isn’t filler itself; it’s how traditional fillers are made and how they’re used. Most HA fillers rely on heat during processing, which fragments the natural hyaluronic acid structure and can lead to stiffer results and more swelling. And too often, filler is used as a shortcut, injected aggressively to create volume that should come from healthy, regenerated tissue. At FACE Medspa, we do things differently. Evolysse uses breakthrough Cold-X™ Technology that preserves the natural HA molecule for softer, more natural movement especially in dynamic areas like smile lines. But here’s what truly sets us apart: we never lead with filler. When using our 3D FACE Approach, we first regenerate your skin from within using growth factors and collagen-stimulating therapies, then apply Evolysse as the final top-off layer. The result is beautifully integrated, naturally refreshed skin not a face that looks filled.”
– FACE Medspa Leadership Team
The First HA Fillers Made With Cold-X™ Technology
Evolysse is a next-generation line of injectable hyaluronic acid (HA) dermal fillers featuring the first-ever Cold-X™ Technology. Hyaluronic acid is a sugar naturally found in your body that provides hydration, volume, and elasticity. Evolysse gels are injected to temporarily plump dynamic wrinkles caused by aging, facial expressions, or weight loss, smoothing lines while allowing natural movement and expression.
What makes Evolysse remarkable is how it’s made. Where traditional fillers use heat during cross-linking (the process that stabilizes the gel), Evolysse cross-links at near-freezing temperatures. This preserves more of the natural HA structure with less cross-linking agent needed, producing a smoother, more natural look and feel.
Evolysse Form is a firmer, structured gel for deeper volume and folds. Evolysse Smooth is a softer, flexible gel for finer lines and superficial correction. Both are FDA-approved for adults 22+ to correct moderate-to-severe nasolabial folds (smile and laugh lines). A third formulation, Evolysse Sculpt for high cheekbone structure and lift is coming fall of 2026.
Results are visible immediately, smoothing smile lines both in motion and at rest, while keeping your expressions natural.
Preserving Nature’s Own Hydrator
Evolysse works by replenishing hyaluronic acid where aging, expression, and volume loss have taken their toll. But the Cold-X™ process is what makes the difference between filler that looks natural and filler that looks “done.”
Cold-X™ Cross-Linking
Cross-linking occurs at near-freezing temperatures rather than with heat. This preserves the integrity of the natural HA molecule, requires less cross-linking agent, reduces fragmentation of the HA structure, and creates a smoother, more natural foundation.
Dynamic-Area Integration
The cold-processed gel integrates smoothly into tissue that moves frequently, like the area around the mouth. It supports natural facial expressions, avoids the stiff or frozen look, reduces the risk of unnatural lumps or bumps, and maintains softness and elasticity where you move most.
Built-In Comfort
Lidocaine is included in both formulations to ease the injection experience, minimizing discomfort during treatment and supporting a calm, relaxed session.
The Result
Evolysse plumps and smooths immediately while preserving the natural movement of your face. Smile lines soften both when you’re expressing and at rest and because the HA structure stays intact, results look and feel like your own skin, not like something added to it.
Are You Bothered By:
If you’re nodding yes to several of these, Evolysse at FACE may be right for you.
Why Cold-X™ Changes the Conversation
Cold Preservation vs. Heat Degradation
Heat-based processing can degrade or fragment the natural HA structure, potentially leading to a stiffer feel and more swelling. Cold-X™ keeps more of the molecule intact, which is why Evolysse integrates so smoothly into expressive areas.
Clinically Proven Performance
In clinical trials, Evolysse performed comparable or superior to established benchmarks like Restylane-L for nasolabial folds, with lasting results and minimal nodules.
Natural Over “Done”
Because results are visible immediately, there’s less temptation to over-inject chasing instant volume, one of the main causes of the overfilled look. Many patients report less “filler fatigue” and more harmonious facial movement.
Are You Bothered By:
Every face is different, which is why Evolysse offers distinct formulations our injectors layer for personalized results.
This softer, more pliable gel is ideal for finer, more superficial lines, milder smile lines, and perioral lines around the mouth. It offers smooth hydration and natural flexibility in delicate areas, perfect for patients wanting subtle refinement.
This firmer, more structured gel is suited to deeper nasolabial folds and volume restoration in areas needing more structure and contour. It provides reliable lift while preserving natural movement.
The most structured formulation, designed for high cheekbone structure and significant lift and volume support. Providers often combine multiple formulations for layered, customized results tailored to your unique facial anatomy.
Why Our Evolysse Results Are Different
We Don’t Just Fill—We Regenerate, Then Refine
This is what truly separates FACE from every other injector offering Evolysse. Most practices treat filler as the whole solution: inject volume where it’s missing and send you home. We see filler as the final, finishing layer of a much more thoughtful process.
We Lead With Collagen and Elastin Stimulation
Our 3D FACE Approach begins with growth factors and advanced collagen-stimulating treatments to regenerate and restore your skin from within first. Healthy, regenerated tissue provides the foundation, and Evolysse becomes the final top-off layer not the entire fix.
We Poke Less With our Advanced FACE Method
Using cannula technique, we treat an entire area through far fewer entry points often just one smooth entry per zone instead of multiple needle sticks. This minimizes discomfort and reduces bruising risk for a gentler experience.
We Deliver a Truly Pain-Free, Low-Downtime Experience
Our exclusive FACE Method reduces bruising, pain, and side effects by up to 80%. We’re known for pain-free experiences with little to no downtime, so you can return to daily life quickly and comfortably.
We Think Holistically and Naturally
Backed by over 20 years of industry-leading expertise, we specialize in injectable collagen and elastin stimulation therapies skillfully combined with premium fillers like Evolysse, for results that look refreshed, harmonious, and authentically you.
Our Award-Winning Injectable Expertise
Our team brings over 20 years of industry-leading skin rejuvenation experience, award-winning injectable artistry, specialization in biostimulation and collagen/elastin therapies, and mastery of advanced cannula technique for comfort and safety.
Your Evolysse Experience:
A quick in-office session often takes 15-30+ minutes. Comfort measures include the lidocaine built into the formula, and The FACE Method technique for fewer pokes. Most patients experience minimal discomfort thanks to our exclusive approach, with minimal downtime, resuming normal activities immediately.
During Treatment:
You’ll relax while our injector uses our advanced technique to treat each zone through as few entry points as possible, often a single smooth entry per area. The lidocaine in Evolysse and our FACE Method work together to keep you comfortable throughout.
After Treatment
Most patients return to normal activities right away. Mild swelling or bruising is less common and typically resolves within a few days. Results are visible immediately and continue settling over the following days, looking natural from the start.
Immediately After Treatment:
You’ll see visible smoothing of smile lines, restored volume and contour, and a natural appearance right away with lines softened both in motion and at rest.
First Few Days:
The gel fully settles, any mild swelling resolves, and results refine into their natural final look.
Long-Term Results:
In clinical studies, improvement lasted up to 12 months for most patients, with roughly 65-72% showing sustained benefits at one year. Individual results vary based on metabolism, area treated, lifestyle, and amount injected. Your provider will design a personalized maintenance plan with periodic touch-ups to sustain your results.
Smile Line Concerns:
For those with moderate-to-severe nasolabial folds and lines that deepen with expression, who want softening without stiffness and natural movement preserved.
Volume Restoration Seekers:
For those who’ve lost facial volume from aging or weight changes, with flattening cheeks or folds, who want lift and contour with a refreshed not overfilled look.
Natural-Results Patients:
For those afraid of looking “done,” who value harmonious facial movement and want refreshment rather than transformation, prioritizing authentic, you-but-better results.
Filler-Experienced Patients:
For those disappointed by stiff results elsewhere or frustrated with swelling and downtime from past fillers, who want a more comfortable, lower-downtime experience with more advanced technology.
Comfort-Conscious Patients:
For those anxious about needles who want fewer entry points, value the pain-free FACE Method, and need to return to life quickly.
The heart of our 3D FACE Approach. We regenerate your skin from within with growth factors and biostimulation first, then top off with Evolysse creating naturally integrated results that look regenerated, not simply filled.
Pairing Evolysse with neuromodulators addresses both static folds and dynamic movement. Filler smooths and restores volume while neuromodulators relax the muscles driving expression lines, for comprehensive, balanced rejuvenation.
Combine the volume and smoothing of Evolysse with laser therapies that address skin tone, texture, and surface concerns treating multiple layers of facial aging in a coordinated plan.
Address skin, volume, and muscle together. Emface tones and lifts underlying facial muscles while Evolysse restores volume and smooths folds, for a complete non-surgical refresh.
FACE Medspa proudly offers FDA-Cleared XERF treatment to patients throughout:
Ready to soften smile lines and restore youthful volume without looking overfilled or frozen? Experience the next generation of HA fillers, applied with the artistry, comfort, and regenerative philosophy that only FACE Medspa offers. Schedule your consultation today and discover what truly natural results feel like.
