What is SKINVIVE™?

Skinvive™ by Juvederm® is the first and only FDA-approved hyaluronic acid (HA) microdroplet
injectable in the US to improve skin smoothness of the cheeks. This product increases hydration
to improve skin smoothness and provide a lasting glow for 6-9 months with optimal treatment.
Also, in a clinical study, patients treated with Skinvive™ reported higher satisfaction with how
glowing, hydrated, refreshed, and healthy their skin looked.

How does SKINVIVE™ work?

Skinvive™ uses the moisture-attracting qualities of the hyaluronic acid molecule to increase
hydration in the skin and improve texture. The droplet injections of Skinvive are placed
superficially, just on the upper layers of your dermis and once it is deposited into the skin, it
diffuses into an even layer of hydration that lasts. Skin hydration develops over the coarse of 2
weeks post treatment.

What is the difference between SKINVIVE™ and other HA fillers?

Essentially, Skinvive™ changes the appearance of your skin, rather than the shape of your face.
Droplet injections of Skinvive are placed superficially (just on the outer layer of your skin, or
your epidermis) to create hydration, whereas other HA fillers on the market are injected into
the dermis to fill in volume loss or augment the shape of your face.
Skinvive also impacts the quality of the skin, unlike other HA fillers, which is the first
breakthrough injectable to accomplish this, and why it the first in class injectable skin booster.

What are the skin benefits of SKINVIVE™?

When Skinvive is injected into the treatment area, it also stimulates collagen production, which
improves elasticity and reduces the appearance of fine lines. By intensely hydrating the
superficial skin, other skin woes like a texture and dullness also improve.

How many syringes of Skinvive™ do I need?

After being on the market in Europe for years, and multiple clinical trials performed, patients
are recommended to have two syringes which come in one box. Many providers may lessen this
amount to save people money, however it is a big mistake, as optimal outcomes were all
achieved with two syringes, as its one syringe needed to hydrate each side of the face. The only
way one syringe could be administered, is just for a very small targeted area.

How long do the results of SKINVIVE™ last?

In clinical studies, patients report satisfaction with the glow of their skin through six months.
Longer studies were done in Europe showing 9 months. A few patients who loved their results,
wanted even more at their one month visit.

Who is a candidate for SKINVIVE™?

Skinvive™ is approved for all Fitzpatrick skin types (I-VI), so anyone looking for a boost can
benefit. Anyone who is noticing skin dullness or is looking to improve cheek smoothness and
increase hydration within the skin to improve skin quality would be a good candidate for
Skinvive™. Anyone who wants to target volume loss, would not be a candidate for Skinvive™


and might be better suited for other HA fillers, however, volume loss and changes in skin
quality are both signs of aging and often go hand-in-hand.

What are the risks with SKINVIVE™?

The risks of Skinvive™ are the same as most other cosmetic injectables, which are mild and
usually temporary, such as swelling, bruising, redness, tenderness, or firmness at or near the
injection site. These temporary side effects typically resolve within days of the treatment. Rare
side effects include skin infection, abrasions, or papules at the injection site.

Is there downtime with Skinvive™?

There is little to no downtime for Skinvive™ treatments. Patients in the clinical studies were
able to resume their daily activities immediately after treatment. Like with Botox or other
injectables, it is recommended to avoid heavy exercise, makeup, and sun exposure for the first
24 hours. You can expect to feel a little lumpy for about a week until the product diffuses
completely through the skin.

When Will I see results from Skinvive™?

You won’t notice the hydration effects from Skinvive™ for about two weeks, unlike filler that
has instant results. You can expect the hydration for 6-9 months.

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*Individual Results May Vary